For medical offices and pharmacies, keeping up with vaccine inventory is essential—but it can also be expensive. Between price fluctuations, manufacturer requirements, and insurance reimbursement challenges, vaccine procurement is one of the most costly and complicated parts of running a healthcare practice.

Fortunately, there are strategic ways to reduce vaccine expenses without sacrificing patient care. At US Physicians’ Purchasing Group (USPPG), we help practices save on vaccine purchases every day. Here are five effective ways to control your vaccine budget while continuing to provide quality care to your patients.

1. Join a Vaccine Buying Group (GPO)

One of the most impactful steps you can take is joining a group purchasing organization (GPO) like USPPG. As a free vaccine buying group, USPPG negotiates preferred pricing with top manufacturers, including GSK and Dynavax, so your practice can access exclusive discounts on essential vaccines like Engerix-B®, Prevnar 20®, ABRYSVO®, Twinrix®, FLUCELVAX®, and more.

By consolidating purchasing power across thousands of members, GPOs lower per-dose costs and eliminate the need to meet high volume thresholds on your own.

2. Monitor Your Inventory Closely

Overordering can lead to expired vaccines—and wasted money. Underordering can result in missed opportunities for patient care. To strike the right balance, implement a system to track vaccine inventory levels and usage trends. Regularly monitor expiration dates and turnover rates to help make smarter purchasing decisions.

Many practices find success with digital inventory tools or assigning one team member to oversee vaccine management.

3. Take Advantage of Combination Vaccines

When medically appropriate, using combination vaccines like Twinrix® (Hepatitis A & B) or Pediarix® (DTaP-HepB-IPV) can reduce the number of injections a patient receives—and lower administrative costs for your practice. Fewer appointments and injections save time and resources for both patients and staff.

Combination vaccines also help improve compliance rates, especially in pediatric and adult patients with multiple vaccine needs.

4. Schedule Bulk Orders Strategically

If your practice administers high volumes of certain vaccines, consider placing larger, less frequent orders to save on shipping fees and qualify for manufacturer incentives. However, be sure to balance bulk ordering with your storage capacity and expiration risk.

Working with USPPG gives you access to expert support in managing vaccine orders across brands and manufacturers—helping you order smarter, not harder.

5. Use Manufacturer Rebates and Payment Terms

Many vaccine manufacturers offer rebates, prompt-pay discounts, or extended payment terms to qualifying practices and pharmacies. These programs can significantly offset your vaccine costs—if you know where to find them and how to qualify.

As a USPPG member, you’ll receive guidance and updates on rebate opportunities and manufacturer incentives so you never miss a chance to save.

Start Saving on Vaccines with USPPG

At USPPG, we make it easy for healthcare professionals to access low-cost vaccines without compromising quality or care. Our free membership gives you exclusive access to contracted vaccine pricing from trusted manufacturers, plus support and resources to streamline your vaccine purchasing process.

Join today and start maximizing your vaccine budget—so you can continue to focus on what matters most: your patients.